We investigated whether baseline nutritional status predicted severe dementia and mortality in a population-based sample. A maximum of three hundred PWD were assessed annually for up to 8. Using Cox proportional hazards models, we examined the association between baseline mMNA score or its subcomponents with each outcome. Covariates included demographics; dementia onset age, type, and duration; APOE genotype; and residency with caregiver. MMNA subcomponents of food group intake, weight loss, BMI, mobility, health status, protein consumption, and mid-arm circumference predicted one or both outcomes. Nutritional status is an important predictor of clinical outcomes in dementia and may provide an avenue for intervention. Dementia is a clinical, usually progressive, syndrome characterized by declines in cognitive and functional abilities resulting in an eventual loss of independence and ultimately, death. Identifying modifiable factors that enhance patient functioning and minimize burden on families and caregivers is an important goal. Recent research has linked nutritional status to cognitive, neuropsychiatric, and functional decline in persons with dementia PWD.
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